[News Feed] Breast Tumors In Mice Eradicated Using Cancer Vaccine

[Forum Mouse]

A team from the University of Pennsylvania School of Medicine has shown that by using a cancer vaccine based on the bacterium Listeria monocytogenes, they can cure mice with established breast tumors. Using Listeria, the researchers, delivered the tumor-associated antigen HER-2/Neu to immune cells. HER-2/Neu is overexpressed in 20 to 40 percent of all breast cancers. These cells eventually enlist killer T cells to destroy the tumor cells that display the HER-2/Neu molecule.

http://www.sciencedaily.com/releases...0915004756.htm